Wireless keyboard and mouse not working after Windows 10 update

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I have a Toshiba PX30T with provided wireless keyboard and mouse on Windows 10. Since the Windows 10 update KB4074588 my wireless keyboard and mouse are not working. I have spent hours on uninstalling and reinstalling the devices, checking the drivers are up-to-date, ensuring the Windows Updates are all installed correctly, rebooting, etc but nothing is working to get my keyboard and mouse back. Any suggestions greatly appreciated.
 
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Wireless implies one is using a nano-transceiver [dongle] in a USB port. I'd be checking the dongle is in a USB 2.0 port rather than in a USB 3.x port, some devices don't always work properly in USB 3.0. And check in Device Manager to see if there are any problems in the USB section.
 
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I assume you have a wired mouse so tht the computer is functional. If not, press the windows key and I in order to access the settings.
Open settings - Update and Security, and select the troubleshooting option. Try the Keyboard and incoming connections. You could also try the "Hardware and devices."
 
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Did any Windows Updates get installed recently? Specifically look for KB4074588 and try removing/uninstalling it. Seems it has a known issue and renders USB and wireless keyboards/mice inoperable.
 

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