Trouble recommends TFC. I've never seen a thorough clean up of temp file that like TFC does.
I find that %temp% works well.
Before you open and clean the Temp Folder; first close any running Windows programs, click Windows key+R. and type %temp% in the Search Box and open the temp folder.
Quite often you'll see a message that says that a particular file(s) can't be deleted, just skip those items and allow Windows to continue deleting the other remaining contents of the "Temp" folder.
When the "TEMP" folder is emptied, restart the computer to allow the changes.